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Search Results to Srinivas Ayyadevara

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Ayyadevara, Srinivas

One or more keywords matched the following items that are connected to Ayyadevara, Srinivas

Item Type	Name
Academic Article	Lifespan and stress resistance of Caenorhabditis elegans are increased by expression of glutathione transferases capable of metabolizing the lipid peroxidation product 4-hydroxynonenal.
Academic Article	Modulation of lipid biosynthesis contributes to stress resistance and longevity of C. elegans mutants.
Academic Article	Prior exposure to oxidized low-density lipoprotein limits apoptosis in subsequent generations of endothelial cells by altering promoter methylation.
Academic Article	Life span and stress resistance of Caenorhabditis elegans are differentially affected by glutathione transferases metabolizing 4-hydroxynon-2-enal.
Academic Article	Reduced kidney lipoprotein lipase and renal tubule triglyceride accumulation in cisplatin-mediated acute kidney injury.
Academic Article	Gene categories differentially expressed in C. elegans age-1 mutants of extraordinary longevity: new insights from novel data-mining procedures.
Academic Article	Lifespan extension in hypomorphic daf-2 mutants of Caenorhabditis elegans is partially mediated by glutathione transferase CeGSTP2-2.
Concept	Carrier Proteins
Concept	DNA-Binding Proteins
Concept	Intermediate Filament Proteins
Concept	Membrane Proteins
Concept	Proteins
Concept	Protein Conformation
Concept	14-3-3 Proteins
Concept	Wnt3A Protein
Concept	Protein Binding
Concept	Protein Multimerization
Concept	Apoptosis Regulatory Proteins
Concept	tau Proteins
Concept	Protein Folding
Concept	Protein Unfolding
Concept	Caenorhabditis elegans Proteins
Concept	Heat-Shock Proteins
Concept	RNA-Binding Proteins
Concept	Extracellular Matrix Proteins
Concept	Intracellular Signaling Peptides and Proteins
Concept	Protein Structure, Secondary
Concept	Recombinant Fusion Proteins
Academic Article	Remarkable longevity and stress resistance of nematode PI3K-null mutants.
Academic Article	Extreme-longevity mutations orchestrate silencing of multiple signaling pathways.
Academic Article	Diverse Caenorhabditis elegans genes that are upregulated in dauer larvae also show elevated transcript levels in long-lived, aged, or starved adults.
Academic Article	Positive feedback between transcriptional and kinase suppression in nematodes with extraordinary longevity and stress resistance.
Academic Article	Proteins in aggregates functionally impact multiple neurodegenerative disease models by forming proteasome-blocking complexes.
Academic Article	Caenorhabditis elegans PI3K mutants reveal novel genes underlying exceptional stress resistance and lifespan.
Academic Article	Age- and Hypertension-Associated Protein Aggregates in Mouse Heart Have Similar Proteomic Profiles.
Academic Article	Proteins that mediate protein aggregation and cytotoxicity distinguish Alzheimer's hippocampus from normal controls.
Academic Article	PIP3-binding proteins promote age-dependent protein aggregation and limit survival in C. elegans.
Academic Article	Proteins that accumulate with age in human skeletal-muscle aggregates contribute to declines in muscle mass and function in Caenorhabditis elegans.
Academic Article	Pericytes and immune cells contribute to complement activation in tubulointerstitial fibrosis.
Academic Article	Aspirin-Mediated Acetylation Protects Against Multiple Neurodegenerative Pathologies by Impeding Protein Aggregation.
Academic Article	Apolipoprotein E4 inhibits autophagy gene products through direct, specific binding to CLEAR motifs.
Academic Article	Structural insights into pro-aggregation effects of C. elegans CRAM-1 and its human ortholog SERF2.
Academic Article	Functional assessments through novel proteomics approaches: Application to insulin/IGF signaling in neurodegenerative disease'.
Grant	Early Events in Alzheimer Pathogenesis
Academic Article	A universal transcriptomic signature of age reveals the temporal scaling of Caenorhabditis elegans aging trajectories.
Academic Article	Aggregate Interactome Based on Protein Cross-linking Interfaces Predicts Drug Targets to Limit Aggregation in Neurodegenerative Diseases.
Academic Article	A Novel Microtubule-Binding Drug Attenuates and Reverses Protein Aggregation in Animal Models of Alzheimer's Disease.
Academic Article	Design and Synthesis of Novel Hybrid 8-Hydroxy Quinoline-Indole Derivatives as Inhibitors of A? Self-Aggregation and Metal Chelation-Induced A? Aggregation.
Academic Article	Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1.
Academic Article	"Protein aggregates" contain RNA and DNA, entrapped by misfolded proteins but largely rescued by slowing translational elongation.
Academic Article	Novel hydroxybenzylamine-deoxyvasicinone hybrids as anticholinesterase therapeutics for Alzheimer's disease.
Academic Article	Intrinsically disordered proteins identified in the aggregate proteome serve as biomarkers of neurodegeneration.
Academic Article	Label-free photothermal disruption of cytotoxic aggregates rescues pathology in a C. elegans model of Huntington's disease.
Academic Article	Glial Fibrillary Acidic Protein: A Biomarker and Drug Target for Alzheimer's Disease.
Academic Article	Machine-learning analysis of intrinsically disordered proteins identifies key factors that contribute to neurodegeneration-related aggregation.
Academic Article	Protein homeostasis in the aged and diseased heart.
Academic Article	Physiological Consequences of Targeting 14-3-3 and Its Interacting Partners in Neurodegenerative Diseases.
Academic Article	Myocardial infarction elevates endoplasmic reticulum stress and protein aggregation in heart as well as brain.
Grant	Neuroinflammation, Protein Aggregates, ApoE4 Drug Targeting, and Autophagy Rescue
Grant	Neuroinflammation, Protein Aggregates, ApoE4 Drug Targeting, and Autophagy Rescue
Academic Article	Leave-one-out-analysis (LOOA): web-based tool to predict influential proteins and interactions in aggregate-crosslinking proteomic data.
Grant	Neuroinflammation, Protein Aggregates, ApoE4 Drug Targeting, and Autophagy Rescue

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GTP Binding Proteins